HIV stigma can now be more dangerous than the virus—research shows how to address this
Credit: Pixabay/CC0 Public Domain Speaking at the 16th International Aids Conference in 2006, the then UNAids executive director, Peter Piot, remarked: “Since the beginning of the epidemic, stigma, discrimination and gender inequality have been identified as major causes of personal suffering, and as major obstacles to effective responses to HIV.” Now, in the fourth decade […]
Previously unknown protein interactions may lead to better HIV treatments
The A3F and A3G interaction results in partial protection of A3F from HIV-1LAI Vif-mediated degradation. HIV-1LAI (LAI) and LAI SLQ mutant (SLQM) viruses were used to determine the Vif-mediated degradation of A3F and A3G. The SLQM is SLQ→AAA and prevents Vif from interacting with Elongin C. Immunoblotting with anti-HA and anti-V5 was used to detect […]
Health groups aim to reach 2 mn people with HIV prevention drug
Credit: Pixabay/CC0 Public Domain Several giant US and international groups focused on fighting HIV and AIDS on Tuesday unveiled a plan to swiftly provide affordable access to a possibly “game-changing” HIV prevention drug in lower-income countries. The Global Fund, a partnership set up to battle AIDS, tuberculosis and malaria, said it had joined forces with […]
New guidelines unveil advanced strategies for HIV treatment and prevention
Credit: Pixabay/CC0 Public Domain On the occasion of World AIDS Day on 1 December 2024, the International Antiviral (formerly AIDS) Society-U.S. (IAS-U.S.) has published new international guidelines for the treatment and prevention of HIV. The updated recommendations were developed by a panel of volunteer medical experts, including Prof Clara Lehmann of the University Hospital Cologne […]
New mechanism found in statin therapy’s heart benefits for HIV
Credit: CC0 Public Domain Investigators who previously found that a daily statin pill helps prevent heart attacks and strokes in people with HIV have now discovered a potential mechanism that may help to stabilize plaques and prevent their rupture in blood vessels. The research led by a team from Mass General Brigham is published in […]
International study shows updated hepatitis B vaccine more effective for people with HIV
Credit: CC0 Public Domain A newer vaccine against hepatitis B virus was clearly superior to an older vaccine type in inducing a protective antibody response among people living with HIV who didn’t respond to prior vaccination, according to the results of an international study led by a Weill Cornell Medicine investigator. The study, reported Dec. […]
Urgent action needed to address alarming rates of sexually transmitted infections in South Africa, says study
HIV (yellow) infecting a human immune cell. Credit: Seth Pincus, Elizabeth Fischer and Austin Athman, National Institute of Allergy and Infectious Diseases, National Institutes of Health Burnet researchers and their collaborators have gained new insights into some of the underlying socio-behavioral and biological factors contributing to the alarmingly high rates of HIV and sexually transmitted […]
Tracking down and eliminating HIV dormant in the body: A major step forward
Graphical abstract. Credit: iScience (2024). DOI: 10.1016/j.isci.2024.111470 Modern therapies help people living with HIV to survive, but scientists are still trying to decipher the deep mystery of how to eventually eradicate the virus for good. Now new laboratory work in Canada sheds light on the vulnerabilities of HIV’s pockets of resistance in the body, and […]
Considerable scale-up needed to achieve 2025 goals for HIV PrEP
Considerable scale-up is needed to achieve the 2025 goals for HIV preexposure prophylaxis (PrEP), according to research published in the Nov. 28 issue of the U.S. Centers for Disease Control and Prevention Morbidity and Mortality Weekly Report. Megan E. Peck, Ph.D., from the CDC in Atlanta, and colleagues examined progress toward the Joint United Nations […]
Vaccines can put an end to HIV. African governments must take the lead in developing them
Credit: Pixabay/CC0 Public Domain HIV remains a major global public health challenge. Nowhere is this more evident than in southern and eastern Africa, where the majority of people living with HIV reside. Here new HIV infections remain alarmingly high despite significant advances in prevention and treatment. In South Africa, an estimated 150,000 people acquire HIV […]
