LPOXY Therapeutics Acquires Assets to Advance C difficile Protection for Antibiotic Patients
Larry D Sutton, MD, PhD, CEO of LPOXY Therapeutics Image credits: LinkedIn LPOXY Therapeutics, Inc has acquired significant assets from Xeno Biosciences Inc to advance its novel therapy for preventing Clostridioides difficile (C difficile) infections in hospitalized patients. The acquisition includes regulatory filings, FDA correspondence, comprehensive CMC data, and intellectual property from Xeno, as well […]
Climate Change is Disrupting Biocontrol of Invasive Spongy Moths
This research connects infectious disease dynamics to ecosystem health by examining how climate change affects the biocontrol of invasive species. The fungal pathogen Entomophaga maimaiga has kept spongy moth populations in check, much like how infectious diseases are controlled in humans. Using disease models designed for humans, researchers analyze how environmental changes impact the spread […]
Doxycycline Postexposure Prophylaxis Prevents STIs Amongst Those Using HIV PrEP
Image credit: Julia Zolotova, Pexels Doxycycline postexposure prophylaxis (doxyPEP) given to people who were receiving HIV preexposure prophylaxis (PrEP) were shown to reduce chlamydia by 79%, syphilis by 80%, and gonorrhea by 12%.1 The study’s results were published in JAMA Internal Medicine. “Among doxyPEP recipients, quarterly chlamydia positivity decreased from 9.6% (95% CI, 9.0%-10.3%) before […]
Entering Peak Norovirus Season as Cases Rise Across the US
Positive Norovirus test results Image credits: CDC Recent CDC data showed a rise in norovirus cases across the US, with more than 22% of tests returning positive as of December 28, 2024, compared to 12% during the same week in December 2023.1 The NoroSTAT report for the 2024–2025 season (August 1–December 11, 2024) recorded 495 […]
The Prospective Value of Genetic Testing for Antifungal Susceptibility for Candida Auris
Image credit: pexels, Pavel Danilyuk Candida auris (C auris) is a concerning fungal infection that continues to see an increase in incidence rates. Since it was first discovered in the United States in 2016, it has grown exponentially. In 2023, there were 4,514 new cases of C auris in the country.1 In addition to rising incidence rates, the fungal […]
Extended Paxlovid Treatment Shows Mixed Results for Long COVID
Alison K Cohen, PhD, MPH Image credits: UCSF A case series published in Communications Medicine explored the effects of extended courses of oral nirmatrelvir/ritonavir (Paxlovid) for individuals with Long COVID. The study involved 13 patients who took extended courses ranging from 7.5 to 30 days. Of these, 11 participants were not experiencing an acute reinfection, […]
Men Experience More Pronounced Health Decline After Lower Respiratory Tract Infections
Image credit: Engin Akyurt, Unsplash A Swedish population-based study finds that older men with lower respiratory tract infections (LRTI) had a greater likelihood of health decline vs men who did not have them. And women did not show any statistically significant differences in health decline. The population was assessed utilizing the Health Assessment Tool (HAT) […]
Simplifying Vaccine Access Translates to Better Uptake
Image credit: Studio Romantic, stock.adobe.com Defined by researchers as a simplification of the vaccination process, they agree that the further overall vaccine access increases, the more eligible patients will actively seek immunization. With the COVID-19 pandemic serving as a prime example of patients independently seeking out vaccination, the authors believe that an infrastructural change in […]
Top 5 Infectious Disease News Stories Week of December 28-January 3
This week, the CDC MMWR highlights a major blastomycosis outbreak and increased tularemia cases, CHOP’s feedback reports improve antibiotic stewardship in pediatric pneumonia, and more. Source link
Survey Reveals African Hesitancy to Get Mpox Vaccination
Image credit: Road Ahead, Unsplash A new survey conducted amongst Africans across 6 countries found that 32.7% of respondents were hesitant to get vaccinated against mpox and for those who were parents, 38.9% were hesitant to get their children vaccinated.1 The results of the survey were published in eClinicalMedicine. “The weighted rates of mpox vaccination […]
