Study Highlights Inappropriate Antibiotic Use for UTIs in Asymptomatic Patients
Whitney Hartlage, PharmD Image credits: LinkedIn A new study has examined the limitations of the current definition of asymptomatic bacteriuria (ASB) in antimicrobial stewardship and revealed that asymptomatic pyuria and/or nitrituria (ASPN) could serve as a more comprehensive marker for unnecessary antibiotic prescribing in urinary tract infection (UTI) treatment. The study analyzed 249 asymptomatic patients […]
Significance of Screening and Industry’s Response
This month marks the 5 year anniversary of the start of the COVID-19 pandemic. On March 13, 2020, the Trump Administration declares a nationwide emergency. Two days later, states begin to implement shutdown orders and schools began closing. This started an arduous journey through a pandemic that caused significant mortality, and great pain and suffering […]
A New Weapon Against Multidrug-Resistant Fungal Pathogens
Zhuo Shang, PhD Image credits: LinkedIn The rising prevalence of multidrug-resistant fungal pathogens has posed a challenge to medical treatment, emphasizing the need for antifungal agents with novel mechanisms of action. Traditional antifungal drugs, such as amphotericin B, have been used for decades but are becoming less effective due to the emergence of resistant strains […]
Hospitals Experiencing Inconsistent Declines in Resistant Infections
Under a magnification of 9560X, this digitally-colorized scanning electron microscopic (SEM) image depicted numerous clumps of methicillin-resistant Staphylococcus aureus (MRSA) bacteria. Image credit: CDC/ Janice Haney Carr/ Jeff Hageman, MHS In a new 10-year analysis, the CDC found antimicrobial resistance in hospitals declined from 2012 to 2019, but rose again during the acute COVID-19 pandemic […]
Zoonotic Hookworm Infection and Cutaneous Larva Migrans
Zoonotic hookworm infection, CLM. Image credits: CDC Zoonotic hookworm infection in humans, commonly presenting as cutaneous larva migrans (CLM), occurs when hookworm larvae, typically from animals like dogs or cats, penetrate human skin. Primarily caused by Ancylostoma braziliense, the larvae migrate through the epidermis, leading to raised, erythematous tracks that often cause intense itching. While […]
The PLF C Diff Summit and Lobby Day
The Peggy Lillis Foundation is hosting its annual National C diff Summit, which is going to be held on Monday, March 31, at the Kellogg Conference Hotel at Gallaudet University in Washington DC. The annual event brings together clinicians, industry, C diff patients, caregivers and other stakeholders. This year’s Summit will feature scientific updates in […]
First-in-Human Study of Long-Acting Injectable HIV Nanoparticle Combination Therapy
Rachel A Bender Ignacio, MD, MPH Image credits: UW UMedicine A first-in-human study has evaluated the safety and pharmacokinetics of a new long-acting injectable antiretroviral therapy (LA-ART), developed as part of the Targeted Long-Acting Combination Antiretroviral Therapy (TLC-ART) Program, a collaboration between US research institutions, including the University of Washington and the National Institute of […]
bioMérieux Receives FDA 510(k) Clearance for its Vitek Compact Pro ID/AST system
Yesterday, bioMérieux announced the FDA cleared the company’s Vitek Compact Pro ID/AST system to be utilized for microorganism identification (ID) and antibiotic susceptibility testing (AST). This system looks to help clinical labs identify infectious diseases and combat antimicrobial resistance, as well as industrial laboratories to identify contaminants for ensuring consumer safety. 1 The Vitek Compact […]
FDA Mid-Month ID Food Recall Safety Updates
Product image Image credits: FDA AKT Trading Inc Recalls Prepared Vegetable Products Due to Clostridium Botulinum Risk AKT Trading Inc of Torrance, CA, recalls prepared vegetable products manufactured by Choshiya Honten Co, Ltd due to potential Clostridium botulinum contamination. The absence of the “Keep Refrigerated” label increases the risk of bacterial growth when stored at […]
Phase 2 Study Shows Efficacy of Six-Month Regimen of Lenacapavir, Teropavimab, and Zinlirvimab for HIV-1
At CROI 2025, Onyema Ogbuagu, MBBCh, FACP, FIDSA, associate professor at Yale School of Medicine, presented key findings from a Phase 2 study evaluating the efficacy and safety of switching to lenacapavir (LEN), teropavimab (TAB), and zinlirvimab (ZAB) (LTZ) every 6 months (Q6M) compared to staying on a stable baseline oral regimen (SBR) in virologically […]
