Peptide-Decorated Liposomes Enhance Drug Delivery Against Candida auris and Candida albicans
Candida auris cells Image credits: Unsplash Candida infections pose a clinical challenge due to the limited availability of antifungal drugs, biofilm formation, and antifungal drug resistance. One promising approach to address these challenges involves the use of fungi-targeted liposomes to enhance drug delivery and solubility while reducing toxicity. In this recent study, researchers developed liposomes […]
An Infection Prevention Method That We Forget?
Handwashing often takes place after encounters with people, using the bathroom, or touching doors or other areas where the public has been utilizing. However, it can be quite a personal decision and one associated with people’s beliefs about germs. A new survey commissioned by the National Foundation for Infectious Diseases (NFID) and released as part […]
Addressing the Infectious Disease Challenges in Immunocompromised Patients
Joshua A Hill, MD, FIDSA, an infectious disease specialist at Fred Hutchinson Cancer Center and the University of Washington Medical Center, is focused on improving care for immunocompromised patients who face risks from infections and are often excluded from clinical research. “Our patient population that we treat here in Seattle at our academic medical centers […]
New Report Calls For Funding Treatments, Greater Emphasis on Chronic Lyme Disease
This deer tick, or blacklegged tick, Ixodes scapularis, as it was questing on a blade of grass. The Lyme disease bacterium, Borrelia burgdorferi, is spread through the bite of infected ticks. The blacklegged tick spreads the disease in the northeastern, mid-Atlantic, and northcentral United States, while the western blacklegged tick, Ixodes pacificus, spreads the disease […]
Safety and Immunogenicity Results for GS-2829 and GS-6779
A Phase 1a study in New Zealand evaluated the safety, tolerability, and immunogenicity of two novel arenaviral vectored vaccines, GS-2829 and GS-6779, for hepatitis B virus (HBV) infection. The study enrolled 51 healthy participants, aged 33 on average, who received varying doses of the vaccines via intramuscular administration to assess safety and immune response. The […]
Another Vaccine-Preventable Disease Seeing a Major Resurgence
Pertussis (whooping cough) is a bacterial infection caused by the bacterium Bordetella pertussis, and is spread through respiratory droplets when an infected person coughs or sneezes.1 In the US, there were 35,435 reported cases of pertussis last year—the highest number in more than a decade. For comparison, there were 7,063 cases in 2023.2 Through the […]
Global Study Reports 98.9% SVR with SOF/VEL in Over 7,000 Hepatitis C Patients
A multinational real-world study of 7,027 patients treated with sofosbuvir/velpatasvir (SOF/VEL) for hepatitis C virus (HCV) infection reported a sustained virologic response (SVR) rate of 98.9%. “We’re really excited to share this data at EASL this year,” said Anu Oshinusi, MD, MPH, vice president of clinical research for hepatitis, respiratory, and emerging viruses at Gilead […]
Greater Incidence of Antimicrobial Resistant Infections in Cancer Outpatients
Image credit: Ivan Samkov, Pexels Outpatients with cancer were found to be at a greater risk of bacterial infections compared to those without it, according to a new study published in The Lancet Oncology. “The rates and corresponding (IRRs) [Incidence Rate Ratios] of AMR pathogens per 1000 isolates was also higher in patients with cancer […]
Colonoscopic Administration of Rebyota Shows Effectiveness for Preventing Recurrent C difficile Infection
A phase 3b clinical trial has demonstrated that fecal microbiota, live-jslm (RBL), delivered via colonoscopy is a safe and effective treatment for preventing recurrent Clostridioides difficile infection (rCDI) in adults. The CDI-SCOPE study, presented at Digestive Disease Week 2025, conducted at 12 US sites, enrolled 41 adults with a history of rCDI who had recently […]
When Will the Measles Outbreak End?
The Johns Hopkins Bloomberg School of Public Health’s Center for Outbreak Response Innovation has a measles outbreak tracker. Much like they did during the COVID-19 pandemic, and were tracking cases of the virus, the institution is tracking measles cases across all states.1 As of today, May 13, there are 1,014 cases of measles across 31 […]
