With its Global Bacterial Meningitis Guidelines, WHO Aims to Speed Up Diagnosis, Treatment
Last month, the World Health Organization (WHO) published its first-ever global guidelines for meningitis diagnosis, treatment and care, aiming to speed up detection, ensure timely treatment, and improve long-term care for those affected. By bringing together the latest evidence-based recommendations, the guidelines provide a tool for reducing mortality and disability caused by the disease.1 The guidelines […]
Maternal RSV Vaccines Show Promise for Infant Protection but Raise Safety Concerns
Maternal RSV vaccines have shown effectiveness in preventing lower respiratory tract infections and RSV-related hospitalizations in infants, according to a new meta-analysis presented at the 2025 Annual Conference on Vaccinology Research. However, safety concerns associated with one vaccine candidate have led to calls for enhanced monitoring in future maternal vaccine trials. The study, led by […]
How Typhoid Fever Triggers Severe Neurological Symptoms
Image credit: Adobe Stock About 15% of patients with typhoid fever develop serious neurological complications, including delirium and seizures, that are collectively described as acute encephalopathy. Until now, however, scientists have not clearly understood the mechanisms behind these life-threatening neurological effects. A new Yale study published May 8 in the journal Nature Microbiology provides critical insights […]
FDA Approves Novavax COVID-19 Vaccine
The FDA has approved the Biologics License Application (BLA) for Novavax’s NVX-CoV2601 (Nuvaxovid) vaccine for active immunization to prevent COVID-19 caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in adults 65 years and older and individuals 12 through 64 years who have at least 1 underlying condition that puts them at high risk for […]
Top 5 Infectious Disease News Stories Week of May 10 to May 17
Microbiota-Based Therapy Improves Mental Quality of Life in rCDI Trial A phase 3b trial presented at Digestive Disease Week 2025 showed that colonoscopic administration of fecal microbiota live-jslm (Rebyota or RBL) is a safe and effective method for preventing recurrent Clostridioides difficile infection in adults. In the open-label CDI-SCOPE study involving 41 participants across 12 […]
Persistent Strain of E coli That Caused Multiple Outbreaks Identified
Last year, E coli O157 outbreaks were linked to romaine lettuce and McDonald’s onions. For the outbreak related to the lettuce, it sickened 89 people across 15 states, with 74 cases having available outcome information. Thirty-six people were hospitalized, with 7 experiencing kidney failure. There was 1 death attributed to the outbreak. For the outbreak associated with […]
Can Diagnostics Aid in Alleviating Antimicrobial Resistance and Sepsis?
Antimicrobial resistance (AMR) continues to be an increasingly significant public health issue, leading to higher mortality rates. One study estimated that bacterial AMR was directly responsible for 1.27 million global deaths in 2019 and contributed to 4.95 million deaths.1 Untreated or undertreated bacterial infections are a major cause of sepsis—a serious complication that places a […]
High Vaccine Acceptance in Sierra Leone Highlights Role of Trust, Messaging, and Misinformation
More than 80% of adults in Sierra Leone said they would accept COVID-19 vaccines for themselves or their families, according to a study presented at the 2025 Annual Conference on Vaccinology Research. The study surveyed 2,146 adults to assess vaccine awareness, acceptance, and hesitancy. Researchers from Emory University, the University of Siena, and other institutions […]
Overcoming Barriers and Embracing Long-Acting PrEP
Zandraetta Tims-Cook, MD, MPH, an infectious diseases physician focused on HIV health disparities in Atlanta, has dedicated her career to HIV prevention and outreach, particularly for women living with HIV. Since 2008, she has worked to bridge gaps in care and improve prevention strategies for high-risk populations. In our interview, Tims-Cook discussed overcoming barriers to […]
Investigational Long COVID Therapy Enrolls First Phase 2 Participant
Carson City, Nevada-based NevBiovie announced today it has enrolled its first participant for it phase 2 clinical trial, ADDRESS-LC, which will study its investigational therapy, bezisterim, and will evaluate its safety and efficacy on motor and non-motor symptoms in patients who have not been treated with carbidopa/levodopa. “This trial will explore whether targeting these mechanisms […]
