Nevada Human Case, D11 Genotype in Dairy Cattle in the State
Colorized transmission electron micrograph of avian influenza A H5N1 virus particles (yellow/red), grown in Madin-Darby Canine Kidney (MDCK) epithelial cells. Microscopy by CDC; repositioned and recolored by NIAID. Image credit: CDC and NIAID The Central Nevada Health District has confirmed the state’s first human case of highly pathogenic avian influenza (HPAI) H5N1 in an adult […]
Over 2 Million Items Recalled Amid Listeria and Salmonella Outbreaks
Donut from Dunkin’ Image credits: Unsplash The FDA has announced a Class II recall affecting 2,017,614 baked goods from FGF, LLC, a pastry wholesaler based in Brownsburg, IN. The recall, initiated due to potential contamination with Listeria monocytogenes, impacts 60 types of products, including plain cake donuts, chocolate cake donuts, apple fritters, yeast ring donuts, […]
Advancements in Targeted Therapies for Infectious Diseases
Image credit: Volodymyr Hryshchenko, Unsplash Infectious diseases remain a major global health threat, with bacteria, viruses, fungi, and parasites evolving resistance to conventional treatments. Antibiotics, antivirals, and antifungals have saved millions of lives, but the growing challenge of antimicrobial resistance (AMR) demands precise, innovative, and highly targeted therapies.1 Instead of traditional broad-spectrum drugs, researchers are […]
Federal Government Changes May Influence Avian Influenza Surveillance and Disease Prevention
With the avian influenza circulating greatly in animals including birds, cattle, and cats, one of the bigger concerns around this is how severe and virulent the virus could become—if given the right settings and circumstances—and this goes from a mostly animal-to-animal transmission to zoonotic transmission to finally one that jumps from person-to person. “We’ve had […]
endTB Trial Paves Way for Shorter, Cheaper, and Safer Rifampin-Resistant TB Treatments
A phase 3 trial has shown that certain 9-month all-oral regimens are as effective as the standard 18-24 month treatment for fluoroquinolone-susceptible, rifampin-resistant tuberculosis (RR-TB). The trial’s primary endpoint was a favorable outcome at week 73, defined by negative sputum cultures or improvements in bacteriological, clinical, and radiological measures. The study found that four of […]
Five All-Oral Regimens Show Efficacy in the Phase 3 endTB Trial for Rifampin-Resistant TB
A phase 3 trial has shown that certain 9-month all-oral regimens are as effective as the standard 18-24 month treatment for fluoroquinolone-susceptible, rifampin-resistant tuberculosis (RR-TB). The trial’s primary endpoint was a favorable outcome at week 73, defined by negative sputum cultures or improvements in bacteriological, clinical, and radiological measures. The study found that four of […]
Top 5 Infectious Disease News Stories Week of February 1-8
Children with Invasive Candidiasis Do Well After Switching IV Antifungal to Enteral A study on children with invasive candidiasis found that transitioning from intravenous (IV) antifungal treatment to enteral therapy was as effective as completing the full IV course, with 99% of those who transitioned having successful treatment outcomes. The shift to enteral therapy reduced […]
FDA Advises Restaurants and Retailers Not to Serve or Sell Certain Oysters
The FDA has issued an advisory for both restaurants and retailers to not sell or serve or sell a specific oyster harvest as they may be contaminated with norovirus. The oysters in questions were harvested from Louisiana Area 3 from 1/10/2025 through 2/4/2025. The oysters were shipped to distributors and retailers in AL, FL, LA, MD, […]
FDA Approves Aztreonam and Avibactam for Complicated Intra-Abdominal Infections
The FDA has approved aztreonam and avibactam (Emblaveo) as the first and only fixed-dose, intravenous, monobactam/β-lactamase inhibitor combination antibiotic. It is approved in combination with metronidazole, for patients 18 years and older who have limited or no alternative options for the treatment of complicated intra-abdominal infections (cIAI). This includes the following Gram-negative pathogens: Escherichia coli, Klebsiella pneumoniae, Klebsiella […]
Study Links Genetic Variations in Cryptococcus neoformans to Disease Outcomes
A study published in Nature Communications has revealed how genetic variations within Cryptococcus neoformans, the pathogen responsible for cryptococcal meningitis, impact patient outcomes. Using a mouse model, the researchers focused on the sequence type 93 (ST93) clade, which includes two subpopulations: ST93A and ST93B. The findings highlight how genetic differences between these subpopulations influence virulence […]
