RNA Medicines and Therapies Drive Healthcare Innovation

RNA-based medicines have revolutionized modern healthcare, offering new solutions for infectious diseases, cancer, and global health threats. To explore the future of this rapidly advancing field, we spoke with Kate Broderick, MD, chief innovation officer at Marawi Life Sciences, a company specializing in RNA and DNA medical innovations. Reflecting on recent developments, Broderick emphasized the […]

Global Guideline on Candidiasis, Part I: Diagnostics

A new guideline for diagnosing and managing candidiasis from the European Confederation for Medical Mycology (ECMM) addresses emerging pathogens such as C auris, and considers application of recently developed diagnostics and newly licensed antifungals.1 This first of a 2-part report describes guideline diagnostic considerations, with part 2 conveying treatment recommendations. The guideline was developed by […]

New insights into Chlamydia trachomatis LGV diversity may help curb STI spread

New insights into Chlamydia trachomatis LGV diversity may help curb STI spread Image Credit: © Khunatorn – © Khunatorn – stock.adobe.com. This article was originally published on our sister site, ContemporaryOB/GYN Diversity within the ompA-genotype L2b clade has been highlighted, increasing understanding of pathogens linked to sexually transmitted infections (STIs) that may reduce their spread, […]

Updates in the Treatment of Mycobacterium Tuberculosis

Tuberculosis (TB) continues to be a significant source of morbidity and mortality. In 2023, 10.9 million people globally contracted TB, and 1.25 million people worldwide died from TB.1 In the United States, in 2023, 9,633 cases of TB were reported, a 15.6% increase compared to 2022.2 TB can be divided into drug-susceptible TB and drug-resistant […]

Top FDA Approvals and Updates from February 2025 in Infectious Disease

FDA Approves Bavarian Nordic’s Chikungunya Vaccine or Those 12 and Older The FDA has approved Bavarian Nordic’s Vimkunya vaccine, the first virus-like particle (VLP) single-dose vaccine for chikungunya, for individuals aged 12 and older. Approval was based on positive phase 3 trial results, where up to 97.8% of participants developed neutralizing antibodies within 21 days. […]

Machine Learning Validates Guidelines for Treating UTI

Image credit: Tara Winstead, Pexels Analyses based on machine learning-derived, or on infectious diseases expert-curated confounders agree that guidelines for treating uncomplicated urinary tract infection, last issued by the Infectious Diseases Society of America (IDSA) in 2011, remain valid despite changes in epidemiology since their release. Sanjat Kanjilal, MD, MPH, Department of Population Medicine, Harvard […]

Top 5 infectious Disease News Stories Week of February 22-March 1

IDSA Makes Statement on HHS Changes to Vaccine Policy, Postponement of Vaccine Meeting The Infectious Diseases Society of America (IDSA), led by Tina Tan, MD, FIDSA, FPIDS, FAAP, expressed concern over recent changes to vaccine policy under the Department of Health and Human Services (HHS), following Robert Kennedy Jr.’s appointment as Secretary. These changes include […]

WHO Releases 2025-2026 Influenza Vaccine Recommendations

Today, the World Health Organization (WHO) announced its recommendations for the viral composition of influenza vaccines for the 2025-2026 season in the northern hemisphere. The announcement was made at an information session at the end of a 4-day meeting on the Composition of Influenza Virus Vaccines, a meeting that is held 2 times per year.1 WHO […]

Adaptation of WHO AWaRe Classification Supports UK’s National Stewardship Priorities

WHO AWaRe Book Image credits: WHO A modified Delphi approach led to the development of a UK-adapted version of the WHO’s AWaRe (Access, Watch, Reserve) antibiotic classification, designed to align with national antimicrobial stewardship (AMS) priorities. This adaptation supports efforts to improve antibiotic use across primary and secondary care settings in the UK. In a […]

The 2024-2025 COVID-19 Vaccine Show Limited Efficacy in Adults

cdc logo: Image credit: CDC In this week’s Centers for Disease Control’s (CDC) Morbidity and Mortality Weekly Report, shows limited efficacy in preventing emergency department visits for adults and a better efficacy in immunocompromised adults. “Vaccine effectiveness (VE) of 2024–2025 COVID-19 vaccine was 33% against COVID-19–associated emergency department (ED) or urgent care (UC) visits among […]