FDA and CDC Recommend Pause on Chikungunya Vaccine IXCHIQ for Adults 65 and Older

Chikungunya vaccine Image credits: Unsplash The US Food and Drug Administration (FDA) and Centers for Disease Control and Prevention (CDC) have jointly recommended a pause in the use of Valneva’s single-dose chikungunya vaccine, IXCHIQ, for individuals aged 65 and older. This precautionary measure follows reports of serious adverse events (SAEs) in elderly individuals with underlying […]
Microbiota-Based Therapy Improves Mental Quality of Life in rCDI Trial

A new analysis from a phase 3 clinical trial presented at this year’s Digestive Disease Week conference in San Diego, California, shows that a live biotherapeutic used to prevent recurrent Clostridioides difficile infection may also improve patients’ mental quality of life, with outcomes correlating to shifts in the gut microbiome and metabolome. Patients who received […]
Vir Biotechnology Announces Results of its Potential Hepatitis B Cure Combination Therapy

Vir Biotechnology, a clinical-stage immunology company, announced results from its MARCH phase 2 trial, which showed the proportion of participants with undetectable hepatitis B surface antigen (HBsAg) at 24 weeks post-end of treatment, was achieved by 17% (3/18) and 21% (3/14) of participants with baseline HBsAg<1,000 IU/mL who were receiving tobevibart and elebsiran without or […]
Ocular Syphilis and Neurosyphilis in a Patient Living With HIV

Ocular syphilis with optic disc neovascularization Final diagnosis Ocular syphilis and concurrent neurosyphilis History of the Present Illness A 50-year-old man with a medical history notable for HIV/AIDS and a history of previously treated neurosyphilis presented with acute on chronic bilateral visual changes. The patient was in his usual state of health until 6 months prior […]
Chikungunya in the Region of the Indian Ocean – Level 2 – Level 2 – Practice Enhanced Precautions – Travel Health Notices | Travelers’ Health
Chikungunya disease is caused by the chikungunya virus and is spread to humans through mosquito bites. Outbreaks have occurred in countries in Africa, Americas, Asia, Europe, the Caribbean, and Indian and Pacific Oceans. Most people infected with chikungunya virus develop some symptoms. Symptoms of chikungunya usually begin 3–7 days after a bite by an infected […]