Hepatitis E Vaccine Demonstrates High Efficacy in Outbreak Setting
Andrew Azman, PhD Image credit: Johns Hopkins Bloomberg School of Public Health During a hepatitis E outbreak in 2022 in South Sudan at the Bentiu refugee camp, the Hecolin HEV vaccine was shown to be highly protective. The results were published in The Lancet Infectious Diseases. “In the primary analysis we estimated an unadjusted two-dose […]
HIV: Genetic characteristics associated with sustained HIV remission after stopping treatment
Tackling HIV continues to be a major public health challenge, mainly because the persistence of viral reservoirs means that people living with HIV need to take lifelong antiretroviral treatment. But some individuals, known as “post-treatment controllers,” are able to maintain an undetectable viral load even after stopping treatment. In a study funded by ANRS Emerging […]
Addressing Gaps in Patient Knowledge and Practices Regarding Fungal Infections
Candida, a common fungal infection. A recent study, published in Nature, revealed significant gaps in patients’ knowledge, attitudes, and practices (KAP) regarding superficial fungal infections, highlighting the urgent need for public health interventions and patient education. Conducted between October 2023 and March 2024, the cross-sectional study assessed 456 patients. Key findings showed that 32% of […]
Shifting Sands in Cellulitis
Skin and soft tissue infections (SSTIs) are common, with an incidence of 77.5 per 1000 person-years of observation, which appears stable over time.1 Recurrences occur in more than 25% of patients with an initial episode, and the mean cost per SSTI episode is $3334.1 Unfortunately, treatment failure occurs in nearly 1 in 5 patients with […]
Azithromycin Helps Reveal a Malaria Parasite Weakness
The antibiotic azithromycin can help identify a critical protein involved in malaria parasite survival by disrupting the division of a vital organelle. Researchers discovered a previously uncharacterized protein in Plasmodium falciparum, now named PfAnchor, that is essential for dividing and inheriting the apicoplast, an organelle required for parasite replication. The apicoplast is a non-photosynthetic plastid […]
Syphilis Exposure During Pregnancy and Childhood Hospital Admissions
This cohort study compares rates of all-cause hospitalization in children exposed to syphilis during pregnancy vs those unexposed in a population-based Brazilian cohort. Source link
