Investigational Phage Therapy Shows Positive Topline Results for Diabetic Foot Osteomyelitis
Phage 3D imageImage credit: Victor Padilla-Sanchez, PhD Yesterday, an Israeli-based company, BiomX, announced results from its phase 2 trial studying its investigational phage therapy, BX211, which was found to be safe, well-tolerated, and demonstrated a clinical benefit for treatment of diabetic foot osteomyelitis (DFO) associated with Staphylococcus aureus.1 Specifically, BX211 produced a sustained and statistically significant […]
Infectious Disease Treatments on FDA’s Watchlist for Q2 2025
As we enter the second quarter of 2025, the FDA is reviewing treatments in infectious disease. Novavax is seeking full approval for its COVID-19 vaccine, Merck’s monoclonal antibody for RSV prevention is under review, and Innoviva has applied an oral antibiotic for gonorrhea. Here is what to expect in the coming months. Novavax COVID-19 VaccinePDUFA […]
Mpox could become a serious global threat, scientists warn
Mpox has the potential to become a significant global health threat if taken too lightly, according to scientists at the University of Surrey. In a letter published in Nature Medicine, researchers highlight how mpox — traditionally spread from animals to humans — is now showing clear signs of sustained human-to-human transmission. Mpox is a viral […]
WHO Issues First Reports on Diagnostics, Therapies For Fungal Infections
Today, the World Health Organization (WHO) announced it had published 2 reports regarding therapies and diagnostics for fungal diseases. The reports were designed to address the gaps in testing and treatments, especially in low- and middle-income countries (LMICs). “Invasive fungal infections threaten the lives of the most vulnerable but countries lack the treatments needed to […]
Humanizing Monoclonal Antibodies for Mucormycosis Treatment
Researchers have developed VX-01, a humanized monoclonal antibody designed to target mucormycosis, a severe fungal infection predominantly affecting immunocompromised individuals. VX-01 enhances the host’s immune response and prevents fungal angioinvasion, offering a promising adjunctive treatment for this often fatal disease. Mucormycosis, caused by Mucorales fungi, poses significant risks, especially to those with weakened immune systems. […]
Early Release – Real-Time Use of Mpox Genomic Surveillance, King County, Washington, USA, 2022–2024 – Volume 31, Supplement—April 2025 – Emerging Infectious Diseases journal
Disclaimer: Early release articles are not considered as final versions. Any changes will be reflected in the online version in the month the article is officially released. Kathryn M. Lau , Michaela Banks, Kaila Bryant, Joanie D. Lambert, Laura Marcela Torres, Stephanie M. Lunn, Cory Yun, Pavitra Roychoudhury, B. Ethan Nunley, Jaydee Sereewit, Alexander L. Greninger, […]
Early Release – Strategies and Opportunities to Improve Community Health through Advanced Molecular Detection and Genomic Surveillance of Infectious Diseases – Volume 31, Supplement—April 2025 – Emerging Infectious Diseases journal
Disclaimer: Early release articles are not considered as final versions. Any changes will be reflected in the online version in the month the article is officially released. Author affiliation: Author affiliation: Centers for Disease Control and Prevention, Atlanta, Georgia, USA Advanced molecular detection (AMD) is the integration of next-generation pathogen sequencing, epidemiologic, and bioinformatics […]
Infectious Diseases Primer for Primary Care: Online
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