IMUNON’s IMNN-101 Vaccine Shows Promising Results in Phase 1 Trial, Demonstrates Cross-Reactivity Against COVID Variants

IMUNON, Inc, a clinical-stage company focused on developing non-viral DNA-based immunotherapies, has announced promising results from its Phase 1 proof-of-concept clinical trial of IMNN-101, a DNA plasmid vaccine targeting COVID-19. The vaccine, developed using the company’s proprietary PlaCCine technology, demonstrated a sustained immune response with a 2- to 4-fold increase in neutralizing antibody (NAb) titers […]
Measles-Positive New Mexico Resident Dies, Cause of Death Still Unconfirmed

This is a developing story and will be updated as more information becomes available. Update March 7, 1:01pm ET: The Texas Department of State Health Services is reporting there have been 198 cases of measles confirmed since late January. Twenty-three of the patients have been hospitalized.1 This means since Texas authorities last reported the number […]
An aerosol test for airborne bird flu

Recent outbreaks of highly pathogenic avian influenza (also known as bird flu) have created a need for rapid and sensitive detection methods to mitigate its spread. Now, researchers in ACS Sensors have developed a prototype sensor that detects a type of influenza virus that causes bird flu (H5N1) in air samples. The low-cost handheld sensor […]
Insights from Investigator Evaluating Paxlovid’s Effectiveness in Vaccinated Older Adults

Katherine L Kahn, MD Image credits: UC Health Randomized clinical trials of nirmatrelvir-ritonavir (Paxlovid) have shown reduced COVID-19-related hospitalizations in unvaccinated individuals, but its effectiveness in vaccinated populations remains unclear. This question is particularly important for older adults, who are at higher risk for severe COVID-19 outcomes. In an exclusive interview with investigator Katherine L […]
Communicable disease threats report, 1 – 7 March 2025, week 10

This issue of the ECDC Communicable Disease Threats Report (CDTR) covers the period 1 – 7 March 2025 and includes updates on cholera associated with holy well water from Ethiopia, chikungunya, Avian flu detected in cats, SARS-CoV-2 variant classification, an overview of respiratory virus epidemiology in the EU/EEA, measles, Ebola, and MERS. Source link
Early Release – Alistipes Bacteremia in Older Patients with Digestive and Cancer Comorbidities, Japan, 2016–2023 – Volume 31, Number 4—April 2025 – Emerging Infectious Diseases journal

Disclaimer: Early release articles are not considered as final versions. Any changes will be reflected in the online version in the month the article is officially released. Alistipes is an anaerobic bacterium rarely detected in clinical samples. Initially described as a bile-resistant, pigment-producing, gram-negative bacillus (1,2), Alistipes was classified as a new genus in 2003 […]
Early Release – Prevalence of Herpes B Virus in Wild Long-Tailed Macaques, Thailand, 2018–2024 – Volume 31, Number 4—April 2025 – Emerging Infectious Diseases journal

Disclaimer: Early release articles are not considered as final versions. Any changes will be reflected in the online version in the month the article is officially released. Krittiga Sapkanarak, Jiro Yasuda, Murasaki Amano, Suthirote Meesawat, Taratorn Kemthong, Titiporn Kaikaew, and Suchinda Malaivijitnond Author affiliation: Chulalongkorn University, Bangkok, Thailand (K. Sapkanarak, T. Kaikaew, S. […]