Immune ‘fingerprints’ aid diagnosis of complex diseases

Your immune system harbors a lifetime’s worth of information about threats it’s encountered — a biological Rolodex of baddies. Often the perpetrators are viruses and bacteria you’ve conquered; others are undercover agents like vaccines given to trigger protective immune responses or even red herrings in the form of healthy tissue caught in immunological crossfire. Now […]

Polio Vaccine Campaign Continues in Gaza Strip, Update on New Cases

Last week, the WHO announced it was continuing its polio vaccine campaign in the war-torn Gaza Strip. The mass vaccination campaign is ongoing right now through Wednesday. The novel oral polio vaccine type 2 (nOPV2) will be administered to over 591,000 children under 10 years of age to protect them from the disease. This campaign […]

As dengue spreads, researchers discover a clue to fighting the virus

Children who experience multiple cases of dengue virus develop an army of dengue-fighting T cells, according to a new study led by scientists at La Jolla Institute for Immunology (LJI). The findings, published recently in JCI Insights, suggest that these T cells are key to dengue virus immunity. In fact, most children who experienced two […]

Scientists invent new drug candidates to treat antibiotic-resistant bacteria

There’s an arms race in medicine — scientists design drugs to treat lethal bacterial infections, but bacteria can evolve defenses to those drugs, sending the researchers back to square one. In the Journal of the American Chemical Society, a University of California, Irvine-led team describes the development of a drug candidate that can stop bacteria […]

A Tool for STI Prevention and Its Implementation

Jaime Garcia-Iglesias, PhD Image credits: LinkedIn Doxycycline post-exposure prophylaxis (DoxyPEP) has emerged as a promising intervention to combat the rising rates of sexually transmitted infections (STIs). As its use gains traction, experts are stressing the need for equitable implementation strategies that prioritize community involvement and address disparities in access. With individuals already adopting DoxyPEP independently, […]

Backyard poultry face bird flu risk when migrating mallards stop to rest

Knowing where, when and for how long mallard ducks — natural carriers of avian influenza — stop and rest as they migrate can help predict the probability that they will spread bird flu to backyard poultry flocks, according to a Cornell University study. The finding, published in Scientific Reports, takes an important step in explaining […]

FDA Declines Invivyd’s EUA Expansion for Pemivibart

The FDA has decided to not expand the existing EUA for Invivyd’s investigational monoclonal antibody (mAb), pemivibart (Pemgarda), to include treatment of mild-to-moderate COVID-19 for immunocompromised persons. The company had been seeking expansion for adults and adolescents who have moderate-to-severe immune compromise due to certain medical conditions such as cancer and organ transplant, and for […]

Antibiotic Resistance in the Context of UTI Treatment Developments

Clinical science in infectious diseases (ID) saw significant progress in 2024, with multiple clinical trials of new antibiotics and infection prevention strategies. The year also brought public health challenges, including outbreaks of antimicrobial resistance, and more, highlighting the continued need for research and clinical interventions.1 At IDWeek 2024, experts gathered to review these developments and […]

Early Release – Efficacy and Safety of 4-Month Rifapentine-Based Tuberculosis Treatments in Persons with Diabetes – Volume 31, Number 3—March 2025 – Emerging Infectious Diseases journal

Disclaimer: Early release articles are not considered as final versions. Any changes will be reflected in the online version in the month the article is officially released. Author affiliation: Centers for Disease Control and Prevention, Atlanta, Georgia, USA (E.V. Kurbatova, W.C. Whitworth, L.P. Peddareddy, N.A. Scott, K.E. Bryant, E. Sizemore, W. Carr); University of […]

Early Release – Maternal and Fetal Implications of Oropouche Fever, Espírito Santo State, Brazil, 2024 – Volume 31, Number 4—April 2025 – Emerging Infectious Diseases journal

Disclaimer: Early release articles are not considered as final versions. Any changes will be reflected in the online version in the month the article is officially released. Author affiliation: Secretaria de Estado da Saúde do Espírito Santo, Vitória, Brazil (J.P. Cola, A.P. Brioschi dos Santos, R. Lubiana Zanotti, A. Endlich da Silva Dela Costa, […]