Addressing the Threat of Candida Infections: Resistance and Management
Oliver Cornely Image credits: CECAD Cologne Candida species are the leading cause of fungal infections in hospitalized patients, contributing significantly to morbidity and mortality. Invasive candidiasis, including candidemia, primarily affects immunocompromised or critically ill individuals, while mucocutaneous candidiasis, such as oral thrush and vulvovaginal candidiasis, can occur in otherwise healthy individuals. While mucocutaneous forms are […]
Recce Pharmaceuticals Reports Positive Data from Phase 2 Study for Gel for ABSSSI
Image credit: Recce Pharmaceuticals Sydney, Australia-based Recce Pharmaceuticals reported positive findings from its phase 2 study examining the efficacy and safety of its topical gel, R327G (RECCE 327), in patients with acute bacterial skin and skin structure infections (ABSSSI), including those with diabetic foot infections (DFI). R327G demonstrated a 93% primary efficacy endpoint over 14 […]
Early Detection of Measles in Wastewater Highlights Silent Transmission Risks
Elke Wollants Image credits: LinkedIn Researchers have identified measles virus genotype D8 in wastewater samples from Brussels, Belgium, raising concerns about silent transmission in the region. The findings highlight the growing role of wastewater surveillance in tracking viral circulation and informing public health interventions. The study analyzed wastewater from Belgian treatment plants and detected measles […]
Investigational Staphylococcus aureus Vaccine Begins Trial
Produced by the National Institute of Allergy and Infectious Diseases (NIAID), this digitally colorized, scanning electron microscopic (SEM) image, depicts a clump of yellow-colored, spheroid shaped, Staphylococcus aureus bacteria that were enmeshed in a blue-colored, filamentous extracellular matrix, which normally binds cells together within the body’s various tissue types. Image credit: National Institute of Allergy […]
Measles Outbreak in Texas Expands to 58 Cases, Hospitalizations Increase
Measles rash Image credits: Unsplash The Texas Department of State Health Services (DSHS) has an updated report of the ongoing measles outbreak in the South Plains region of Texas. As of February 18, 2025, 58 cases have been identified, with symptoms starting within the past three weeks. 13 patients have been hospitalized, and four of […]
FDA Sets PDUFA Date for Lenacapavir For HIV Prevention
This morning, Gilead announced the FDA has accepted its new drug application (NDA) submissions for lenacapavir for the prevention of HIV as PrEP.1 The FDA will review the applications under priority review and has assigned a PDUFA target action date of June 19, 2025. If lenacapavir does get approved, it will be the first and […]
Community Engagement and Data Practices
Observational studies have long played a pivotal role in clinical research and public health responses during epidemics. These studies provide vital data that inform early decisions, particularly in the early stages of an outbreak when time is of the essence. Tthey offer immense value, they also come with challenges, especially regarding data accuracy, relevance, and […]
Wyoming Reports First Case of Avian Influenza
A state official says the woman is hospitalized in another state, and had preexisting health conditions that can make people more vulnerable to illness. Source link
Insights into PCR and Culture-Based Methods
Koos Korsten, MD, PhD, MSc Image credits: LinkedIn Candidozyma auris (Candida auris) is an emerging, potentially multi-drug-resistant pathogen that presents a significant challenge in healthcare settings, particularly in intensive care units and hospital environments. Accurate and timely detection of C auris is crucial for infection control, especially during outbreaks. In this study, researchers compared the […]
FDA Places Hold on Moderna’s Norovirus Vaccine Over a Single Case of Guillain-Barré Syndrome
In Moderna’s quarterly financial reporting released last Friday, the company disclosed their investigational norovirus trivalent vaccine (mRNA-1403) was placed on hold by the FDA after a case of Guillain-Barré syndrome was discovered. It is currently under investigation, and no further information was provided about the person’s condition.1 The 2-season phase 3 study Nova 301 […]
