FDA Approves Aztreonam and Avibactam for Complicated Intra-Abdominal Infections

The FDA has approved aztreonam and avibactam (Emblaveo) as the first and only fixed-dose, intravenous, monobactam/β-lactamase inhibitor combination antibiotic. It is approved in combination with metronidazole, for patients 18 years and older who have limited or no alternative options for the treatment of complicated intra-abdominal infections (cIAI). This includes the following Gram-negative pathogens: Escherichia coli, Klebsiella pneumoniae, Klebsiella […]

Study Links Genetic Variations in Cryptococcus neoformans to Disease Outcomes

A study has uncovered insights into how genetic variations within Cryptococcus neoformans, the pathogen responsible for cryptococcal meningitis, affect patient outcomes. The research focuses on the sequence type 93 (ST93) clade, which includes two subpopulations: ST93A and ST93B. The findings show how genetic differences between these subpopulations influence virulence and immune system interactions. The study […]

American Public Health Association’s Opposition to RFK Jr’s HHS Nomination

This is the third in a series around the intersection of government and public health and how the former can affect the latter. Back on November 18, and shortly after the presidential election, the American Public Health Association (APHA) released a statement opposing the nomination of Robert F. Kennedy Jr for Health and Human Services […]

Early Release – Lessons Learned from Early Implementation and Scale-up of Stool-based Xpert Testing to Diagnose Tuberculosis in Children – Volume 31, Number 3—March 2025 – Emerging Infectious Diseases journal

Lessons Learned from Early Implementation and Scale-up of Stool-based Xpert Testing to Diagnose Tuberculosis in Children Volume 31, Number 3—March 2025 Altmetrics Click a source for Altmetric details What is the Altmetric Attention Score? The Altmetric Attention Score for a research output provides an indicator of the amount of attention that it has received. The […]

Communicable disease threats report, 1 – 7 February 2025, week 6

This issue of the ECDC Communicable Disease Threats Report (CDTR) covers the period 1-7 February and includes updates on Mpox, Shigella sonnei, chikungunya, SARS-CoV-2, Ebola, yellow fever, avian influenza, Middle East respiratory syndrome coronavirus (MERS-CoV) and an overview of respiratory virus epidemiology in the EU/EEA. Source link

New Virus Discovery Highlights Zoonotic Risks in North America

A Shrew. Image credits: Unsplash A study conducted by researchers from Auburn University, University of Queensland, and University of Rochester has discovered a novel henipavirus in northern short-tailed shrews (Blarina brevicauda) in Alabama, US. This discovery, published in Emerging Infectious Diseases, indicates the presence of henipavirus in North America, with potential zoonotic implications.1 The research […]