Ceftolozane Tazobactam Linked to Increased Clinical Success in Pneumonia
The CACTUS study found a 10% improvement in clinical success with ceftolozane tazobactam (CT), which was linked to a 1.5-fold increased chance of clinical success. After adjusting for residual differences between the treatment arms, the likelihood of success was nearly twice as high with CT. Despite these findings, mortality rates were similar between the two […]
HIV stigma can now be more dangerous than the virus—research shows how to address this
Credit: Pixabay/CC0 Public Domain Speaking at the 16th International Aids Conference in 2006, the then UNAids executive director, Peter Piot, remarked: “Since the beginning of the epidemic, stigma, discrimination and gender inequality have been identified as major causes of personal suffering, and as major obstacles to effective responses to HIV.” Now, in the fourth decade […]
Public shows greater acceptance of RSV vaccine as vaccine hesitancy appears to have plateaued
A year after becoming available, vaccines to protect against RSV in newborns and older adults are being more widely accepted by the American public, according to a new Annenberg Public Policy Center (APPC) health survey conducted in November 2024. Over half of U.S. adults (52%) think the vaccine given to pregnant individuals to protect their […]
Previously unknown protein interactions may lead to better HIV treatments
The A3F and A3G interaction results in partial protection of A3F from HIV-1LAI Vif-mediated degradation. HIV-1LAI (LAI) and LAI SLQ mutant (SLQM) viruses were used to determine the Vif-mediated degradation of A3F and A3G. The SLQM is SLQ→AAA and prevents Vif from interacting with Elongin C. Immunoblotting with anti-HA and anti-V5 was used to detect […]
Identifying a Novel Variant of Klebsiella Pneumoniae
Jose Alexander, MD, ABMM, ABAIM, FCCM, CIC, ASCP, BCMAS, medical director for the microbiology laboratory at AdventHealth in Orlando, FL has a unique perspective. As someone who has been both a practicing physician in the past and a current laboratorian, he is able to utilize both his clinical and diagnostic experiences and apply them to […]
Examining COVID-19 Mortality Rates Against Specific Treatments for Inpatients
Image credit: Pexels-rdne As COVID-19 becomes an endemic respiratory pathogen we ultimate contend with, the capacity to treat and manage severe infections and reduce mortality is that much more important. The Centers for Disease Control and Prevention (CDC) noted an age-adjusted 47% decline in deaths from 2021 (when the first vaccines were rolled out) to […]
Contagion Winter 2024 Digital Edition
View our interactive Winter 2024 digital edition. Source link
CDC Report and RECOVER Study Update
Prevalences of current Long COVID (A) and significant Long COVID–associated activity limitation (B) among adults, by jurisdiction — Behavioral Risk Factor Surveillance System, United States, 2023 Image credits: CDC A new report from the CDC, based on data from the 2023 Behavioral Risk Factor Surveillance System (BRFSS), shows that 6.4% of noninstitutionalized US adults reported […]
