mRNA Vaccine Shows Potential for C difficile Infections

Joseph Zackular, PhD, an assistant professor at the Children’s Hospital of Philadelphia and the University of Pennsylvania, is leading research on Clostridioides difficile (C difficile) and the development of an mRNA vaccine. His recent work has shown promise in reducing mortality and improving outcomes for infections caused by this bacterium. In our recent interview, Zackular […]

Investigational Therapeutic for Recurrent C Difficile Reduces Antibiotic Resistant Genes

During the recent ID Week, Vedanta Biosciences shared data on its completed phase 2 CONSORTIUM study. The company reported its investigational live biotherapeutic product, VE303, an investigational treatment for recurrent C difficile was well tolerated, reduced the odds of C diff recurrence by >80% compared with placebo, colonized the gut well, and led to early […]

New guidelines unveil advanced strategies for HIV treatment and prevention

Credit: Pixabay/CC0 Public Domain On the occasion of World AIDS Day on 1 December 2024, the International Antiviral (formerly AIDS) Society-U.S. (IAS-U.S.) has published new international guidelines for the treatment and prevention of HIV. The updated recommendations were developed by a panel of volunteer medical experts, including Prof Clara Lehmann of the University Hospital Cologne […]

Unexplained “Dancing Disease” Affects Women in Uganda

Women in Uganda Image credits: Unsplash Health authorities in Uganda are investigating a mysterious illness, locally referred to as “Dinga Dinga,” a term derived from a local dialect meaning “shaking like dancing.” The disease, which has emerged in Bundibugyo district, is affecting mainly women and girls, leading to symptoms including fever and uncontrollable body shaking. […]